The artist has donated the entirety of his £25,000 Mercury Prize prize money to the MVT, which works to protect the UK's small live music spots.
The star was awarded the cheque on 16 October as his latest record the album was named the best record of the previous year.
Fender has opted to give the cash to the trust, in acknowledgment of the vital role local spots played in his beginning days.
"As an artist wouldn't be doing what I am doing today if it hadn't been for all the performances I did around the region, and elsewhere, when I was just getting going," said Fender. "These spaces are iconic, but they are struggling."
From early 2023 onward, at least 150 of these locations have permanently closed – about 16% of the entire UK sector.
In the last year, well-known musicians like Pulp, Coldplay, Katy Perry and Sheeran have all aided the trust in its initiatives to support the industry, by adding a modest fee to their ticket prices, which benefits independent venues.
He also took part, collecting over £100k on his live tour to support thirty-eight small stages across Britain.
The donation assisted spaces that were confronting potential shutdown due to issues arising from floods, fire incidents and bereavements, as well as licensing issues, conflicts and noise complaints.
Other venues were granted financial assistance in improving amenities and gear that directly benefitted musicians and concertgoers.
"The concept that funds from performances in large arenas backs the local stages, where it kicks off for artists like me, is just common sense," Sam Fender has said.
The musician is far from the only musician to donate his honor winnings to good deeds.
Back when the band earned the prize in the mid-90s for their record the album, vocalist Jarvis Cocker announced that the band would donate their cash to the non-profit War Child.
In 2002, rapper and singer she divided her bounty between a few charities, such as the NSPCC and a Sickle Cell organization.
"Additionally, I contributed a thousand pounds to my local community centre, to their gymnastics class, because I did gymnastics when I was a child and they lacked better apparatus," she shared with outlets.
Two years ago, the band donated their prize money to the local youth club that developed their group, in addition to other independent music bodies.
Also winners that year they gave their award to a MS organization after a close contact was found to have the illness.
"Receiving the award was quite enough," said singer the singer. "The cash was the cherry on top but we could do without the cherry, because we had the main prize. So our success affected the lives of others."
In the past week, the trust announced it had protected a couple of local spots in that region, by transferring them to local control.
The first in that area and the other in the city were bought under the Own Our Venues initiative, which is backed by a national body and music fans who purchase "ownership units" in the venues.